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prEN ISO 11350

Water quality - Determination of the genotoxicity of water and waste water - Salmonella/microsome fluctuation test (Ames fluctuation test) (ISO 11350:2012)

Draft Public enquiry
Comment end date 2025-06-17
Export comments Read draft and comment

Project stage codes

1. Decision on WI Proposal
2. Projektas
3. Viešoji apklausa
From 2025-04-18 till 2025-06-17
4. Closure of enquiry
5. Submission to Formal Vote

Organisation

CEN Europos standartizacijos komitetas

ICS

13.060.70 - Examination of biological properties of water

Technical Committee

TK 36 Environmental protection

ForeignTC'S

CEN/TC 230

Number of comments

0

Comment start date

2025-04-18

Scope

This International Standard specifies a method for the determination of the genotoxic potential of water and waste water using the bacterial strains Salmonella enterica subsp. enterica serotype Typhimurium TA 98 and TA 100 in a fluctuation assay. This combination of strains is able to measure the genotoxicity of chemicals that induce point mutations (base pair substitutions and frameshift mutations) in genes coding for enzymes that are involved in the biosynthesis of the amino acid, histidine.